Diabetes mellitus is a chronic metabolic disorder characterized by persistent hyperglycaemia resulting from impaired insulin secretion, insulin resistance, or both. Type 2 Diabetes Mellitus (T2DM) accounts for the majority of global diabetes cases and continues to rise rapidly, particularly in low- and middle-income countries undergoing socioeconomic transition. India has witnessed a notable epidemiological shift, with T2DM increasingly affecting younger and rural populations due to lifestyle changes, unhealthy dietary habits, physical inactivity, and psychosocial factors. This case report describes a 47-year-old woman with poorly controlled T2DM who presented with progressive fatigue, polydipsia, polyphagia, morning tiredness, weight loss, and recurrent infections. Biochemical assessment revealed markedly elevated HbA₁c (10.2%), consistent with chronic uncontrolled hyperglycaemia. A comprehensive six-month multimodal intervention was initiated, integrating pharmacological management with structured dietary modification, natural supplementation, yoga-based practices, and regular follow-up. The intervention emphasized low-glycaemic, fibre-rich dietary patterns; daily yoga and pranayama; natural supplements including fenugreek, amla, cinnamon, and bitter gourd; and adherence to prescribed metformin and glimepiride. At six months, the patient demonstrated substantial metabolic improvement, with HbA₁c reduced to 6.9%, improved symptom burden, better sleep quality, and weight reduction. This case illustrates the therapeutic value of personalized, holistic, multimodal strategies in improving glycaemic control in T2DM. The outcome reinforces evidence supporting the integration of lifestyle modification, yoga, dietary restructuring, and pharmacotherapy in optimizing metabolic health and preventing long-term complications.