Polycystic Ovary Syndrome (PCOS) is a complex endocrine and metabolic disorder frequently associated with menstrual irregularities, hyperandrogenism, insulin resistance, and polycystic ovarian morphology. Emerging evidence supports yoga as a complementary therapeutic option for improving both physiological and psychological symptoms in women with PCOS. This single-case study reports the therapeutic outcomes of a 16-week specific yogic intervention on ovarian morphology reversal in a 20-year-old woman with long-standing PCOS. The patient presented with irregular menses, weight gain, hair fall, and ultrasonographic findings confirming bilateral polycystic ovaries. With no concurrent pharmacological treatment, she underwent a structured yoga program consisting of Surya Namaskar, Pawanmuktasana Series-I, breathing practices, and guided relaxation for 45–60 minutes per day, five days a week.

Following the 16-week intervention, notable improvements were observed. Menstrual cycles normalized by week twelve, and follow-up ultrasonography showed a reduction in ovarian size from 33 mm to approximately 23 mm, with complete resolution of polycystic features. Her BMI decreased from 27.4 to 26.1 kg/m², and she reported reduced hair fall, improved physical fitness, enhanced energy levels, and lower stress. These findings align with existing research highlighting yoga’s beneficial role in regulating the hypothalamic–pituitary–ovarian axis, improving insulin sensitivity, reducing inflammation, and promoting psychological well-being.

This case supports the potential of yoga as a safe, holistic, and non-pharmacological intervention for managing PCOS and improving ovarian morphology. Larger controlled studies are warranted to confirm these findings and develop standardized yoga protocols for clinical practice.