In humans, the hypertensive effects of adrenocorticotropic hormone (ACTH) infusion are reproduced by intravenous or oral Cortisol. Oral Cortisol increases blood pressure in a dose-dependent fashion. At a dose of 80–200 mg/day, the peak increases in systolic pressure are of the order of 15mmHg. Direct and indirect measures of sympathetic activity are unchanged or suppressed during Cortisol administration, suggesting that cortisol-induced hypertension is not mediated by increased sympathetic tone. Cushing syndrome happens when the body has too much of the hormone cortisol for a long time. This can result from the body making too much cortisol, or from taking medicines called glucocorticoids, which affect the body the same way as cortisol. Hypertension, which is a significant risk factor for cardiovascular disease, is often assessed in clinical settings using reference ranges for various haematological and immunological parameters. Specific haematological parameters, such as red blood cells, red cell distribution width, mean cellular/corpuscular haemoglobin, mean cellular/corpuscular haemoglobin concentration, haemoglobin, haematocrit, mean cellular/corpuscular volume, platelet count, white blood cells, basophils, lymphocytes, neutrophils, monocytes, eosinophils, neutrophil-to-lymphocyte ratio, monocyte-to-lymphocyte ratio, platelet-to-lymphocyte ratio, have a role to play in the development of hypertension. Yoga Therapy is the professional application of the principles and practices of yoga to promote health and well-being within a therapeutic relationship that includes personalized assessment, goal setting, and lifestyle management.

Adapting the essential and important yogic management conveniently and comfortably, one can easily get into the flow chart. Various Sukshma Vyayams, Asanas with proper inhale/exhale sequences, Pranayam, antar kumbaka, bahir kumbaka, meditation, and Savasana are included in the training program for the Pre-hypertensive volunteers. The present study was done to assess the efficacy of selected yoga practices for reducing high blood pressure to a minimum among middle-aged men. The study was performed to study the influence of yogic management on patients with hypertension.

The potential mechanisms of Cortisol action may be relevant in a number of clinical contexts, including Cushing's syndrome, apparent mineralocorticoid excess, the hypertension of liquorice abuse and chronic renal failure. There is also preliminary evidence suggesting a role for Cortisol in essential hypertension. The associated symptoms like stress, depression, anxiety, etc. can also be treated along with hypertension.

Aim & Objectives: To observe the blood pressure variations among hypertensive middle-aged men in experimental and controlled groups, and to propose the yogic management for bringing down the hiked systolic and diastolic blood pressure to the required level. We aimed to find the role of yoga as an efficient tool for rejuvenating the functions of organs involved in the pre-hypertension stages, specially by balancing the serum cortisol levels.

Materials and Methods: 30 patients with pre- hypertension between the ages of 35-50 years were selected. After a rest of 15-20 minutes in a comfortable posture their baseline physiological parameters such as Heart rate(HR) and Respiratory rate(RR). Systolic blood pressure (SBP) and diastolic blood pressure (DBP) were recorded by an automated digital Sphygmomanometer. the cortisol level in the morning hours and the haemoglobin were also earmarked for the study. The controlled group and the experimental group were volunteer to participate and the experimental were given a proper training program.

Results: A significant result was achieved during the research. The cortisol level has come down to the requisite level.

Conclusion: It is evident from the results that yoga plays a vital role in the lifestyle diseases, especially for the Pre-hypertensive men so as to prevent the later stage of hypertension.